Introduction: With the development and widely use of HER2 targeted therapies, HER2 expressing metastatic breast cancer have no longer dismal prognosis as once expected.The combination of HER2 targeted therapies with chemotherapatic agents prolongs overall survival.Pertuzumab is a new monoclonal antibody molecule that binds to the extracellular port
Autologous Platelet- and Extracellular Vesicle-Rich Plasma Is an Effective Treatment Modality for Chronic Postoperative Temporal Bone Cavity Inflammation: Randomized Controlled Clinical Trial
PurposeTo determine the efficacy of autologous platelet- and extracellular vesicle-rich plasma (PVRP) to treat chronic postoperative temporal bone cavity inflammation (CPTBCI) Vanilla Chai after exhausting surgical and standard conservative therapies.Materials and MethodsPatients were randomly allocated to treatment with PVRP (PVRP group) or standa
Factors associated to treatment failure in hypertensive patients requiring hospital admission
Introduction: High blood pressure is a very Shirts frequent disease that, in spite of multiple advances in therapy, continues to be poorly controlled and frequently leads to decompensation requiring hospitalization or emergency services.Objectives:To identify the factors associated to treatment failure in hypertensive patients requiring hospital ad